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Microbicides news

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PrEP
Can a gel to prevent HIV be applied as a lube?

Rectal microbicide gels, applied either daily or before and after sex, are currently being investigated as an option for HIV pre-exposure prophylaxis (PrEP). Given that many people who have anal lready use lube, one hope is for an HIV-prevention product that people could essentially use in place of a lube. But can gels provide enough coverage across rectal tissue if people don’t use an applicator?

Published
18 March 2016
From
BETA blog
Microbicides
NIAID to Fund Further Study of Dapivirine Vaginal Ring for HIV Prevention

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today that it would move forward with an open-label extension study of an HIV prevention tool for women: a silicone ring that continuously releases the experimental antiretroviral drug dapivirine in the vagina. The new study builds on recently announced findings from the ASPIRE trial which found that the dapivirine ring safely provided a modest level of protection against HIV infection in sub-Saharan African women.

Published
14 March 2016
From
National Institute of Allergy and Infectious Diseases
Microbicides
Vaginal ring for HIV prevention: a few details would have elevated good coverage to great

Analysis of BuzzFeed's coverage of vaginal ring studies.

Published
01 March 2016
From
Health News Review
Microbicides
Why a new vaginal ring could be a game-changer in HIV prevention

This is the first time two phase-three clinical trials have confirmed statistically significant efficacy for a microbicide to prevent HIV. The dapivirine ring was designed to offer potentially long-acting protection against HIV through slow, continuous delivery of dapivirine into the vaginal tissues over the course of four weeks. But there are still several more steps that need to be followed before the ring becomes available to women.

Published
01 March 2016
From
The Conversation
Transmission and prevention
Modern HIV Prevention: What’s Next For Women?

The vaginal ring is one more addition to an already exciting array of antiretroviral-based biomedical options in the prevention toolbox that has ushered in a new era in HIV prevention.

Published
26 February 2016
From
International AIDS Society
Microbicides
More investment needed in developing female-controlled HIV prevention options

Results from two large-scale studies of a vaginal ring that releases the antiretroviral medicine dapivirine to prevent HIV among women have shown protection of around 30% against HIV. The results are encouraging and show the urgent need to expand investment in research and development for female-controlled methods of HIV prevention. Although less effective than hoped for, the results are the first to show that a sustained release mechanism for antiretroviral medicine is feasible, safe and partially effective in preventing HIV infection among women. Follow-up studies are needed to build on these results and there is a need to better understand how to optimize the HIV prevention effect and support adherence.

Published
24 February 2016
From
UNAIDS
Transmission and prevention
New tools to fight AIDS

Kenneth Mayer: Despite our great progress, we require better tools to fight AIDS. That is why there is so much excitement around this year’s annual Conference on Retroviruses and Opportunistic Infections, which will convene in Boston Feb. 22-25. We are going to learn more about two emerging tools to control the HIV/AIDS epidemic: prevention medicines that are easy to use and protect those who are HIV negative from infection, and advances in vaccine research.

Published
21 February 2016
From
Boston Globe
HIV prevention policy
Activists United and Ignited by Urgency for HIV Prevention in Europe: EATG and AVAC call for the rollout of PrEP as a proven HIV prevention strategy

Initiated and organised entirely by the community of people living with and at risk for HIV, the second European HIV Prevention Summit brought together representatives of civil society, the pharmaceutical industry, researchers and academia in Brussels between 29 and 31 January. In addition to a thorough examination of PrEP (pre-exposure prophylaxis), the summit discussed the latest developments in the research fields of vaccines, rectal and vaginal microbicides and antibodies and their utility in HIV prevention.

Published
03 February 2016
From
EATG
Microbicides
Microbicide Development Hinges on New Products Administered in New Ways

Non-specific or antiretroviral-based vaginal gels failed to work but new formulations offer hope.

Published
11 January 2016
From
IAVI Report
HIV prevention policy
Will Nutland: The emergence of the end of HIV

Will Nutland proposes that instead of the Hollywood style ‘end of AIDS moment’ fantasy, the end of AIDS will be a process with a number of emerging endpoints. In this eye-opening talk, Will introduces PrEP and rectal microbicides and discusses their efficacy and levels of acceptability. He surmises that the end might happen without us even noticing.

Published
10 November 2015
From
TEDx Talks / You Tube
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.